The impact of volume loss during blood donation on continuous blood pressure measurements in spontaneously breathing subjects.

The impact of volume loss during blood donation on continuous blood pressure measurements in spontaneously breathing subjects. - Volume-BP study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34062

Enrollment

Registered

2010-10-20

Start date

2011-01-15

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vrijwillige bloeddonatie volme loss

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Volunteers giving a blood donation of 500ml full blood.

Exclusion criteria

Exclusion criteria: Body mass index (BMI) 15 35 kg/m2. Diabetes mellitus. Underlying cardiovascular diseases. Use of beta blockers, anti-hypertensive drugs or diuretics.

Design outcomes

Primary

Measure	Time frame
Changes in the pulse pressure during a respiratory cycle after a 500 ml volume loss when compared to baseline in spontaneously breathing subjects.	—

Secondary

Measure	Time frame
Pulse pressure variation (PPV): The percentage change of the pulse pressure during the breathing/respiratory ventilation cycle. Continuous systolic blood pressure (SBP) Continuous diastolic blood pressure (DBP) Mean arterial pressure (MAP) Heart rate (HR) Amount of blood donated in ml (BD) Demographic volunteer variables: age, sex, race, BMI, comorbidities, current medication, intoxications.	—

Countries

Netherlands

Outcome results