GEEN AANDOENING! gezonde hersontwikkeling: hersenfunctie, hersenstructuur en gedrag n.a.
Conditions
Interventions
None listed
Sponsors
Universiteit Leiden
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: See also page 17 in the protocol 1. Healthy children, adolescents and young adults without a history of neurological disorders 2. Right-handed 3. No counter-indications for MRI 4. Native Dutch speakers
Exclusion criteria
Exclusion criteria: 1. Lefthanded 2. A history of psychiatric and/or neurological disorders 3. Counter-indications for MRI (such as metal implants, heart arrhythmia, claustrophobia, and possible pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of these studies is to understand how the developmental changes in different regions of the brain are important for cognitive and emotional decision-making at different stages of development. To this end, we will acquire fMRI, sMRI and DTI data and behavioral responses of participants aged 8-25 years. Furthermore, these studies will be complemented with heart rate and skin conductance measures and with performance outside of the scanner on a battery of tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| The goals of the current set of studies are to use functional Magnetic Resonance Imaging (fMRI) to: 1. Identify brain regions that are associated with developmental changes in functions that may contribute to developmental changes in cognitive and emotional decision-making using three cross-sectional studies 2. Identify the relationship between striatal responsiveness and prefrontal regulatory processing | — |
Countries
Netherlands
Outcome results
None listed