arthrosis joint degeneration osteoarthritis
Conditions
Interventions
Patients will be treated with an external fixator bridging the knee joint. Two
monotubes are placed on bone pines, four pins in the femur and four in the
tibia. The joint is distracted for at least
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 2
Exclusion criteria
Exclusion criteria: Bilateral knee osteoarthritis Joint malalignment > 10° History of infectious arthritis Primarily patello-femoral osteoarthitis Knee instability with physical examination Psychological difficulties which interfer with joint distraction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome parameter will be clinical effectivity determined by the WOMAC questionair on pain, function and stiffness. Structural effectivity will be analysed on x-ray and MR. The treatment with one month distraction is considered effective if three out of four patients have comparable results with the previous study of two months distraction. | — |
Secondary
| Measure | Time frame |
|---|---|
| A secundary outcome parameter is clinical effectivity based on physical examination. There will also be a more specific analysis on biological change of the joint by biomarker and MR analysis. Pin tract infections will be registered and retrospectively compared to the two month distraction study. | — |
Countries
Netherlands
Outcome results
None listed