The incidence of, and risk factors for liver disorders related to drugs

The incidence of, and risk factors for liver disorders related to drugs - Hepatotoxicity

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33992

Enrollment

Registered

2009-10-26

Start date

2009-10-26

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Induced Liver Injury

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients who present themselves to the GP with clinical symptoms and complaints which could be related to liver damage, and who have at least òr an ALAT value of >2 times the normal value, òr who have a combination of a raised ASAT, alkalic phosfatase, and bilirubin, where at least one of these 3 had to be >2 times the normal value

Exclusion criteria

Exclusion criteria: cancer/carcinoma, liver injury or another form of hepatitis, cholelithiasis, cholecystitis, acute or chronic pancreatitis, heart failure, alcohol abusus, HIV infection, medical history

Design outcomes

Primary

Measure	Time frame
Incidence of drug induced liver disorders in an unselected population in general circumstances. Relative risk of certain liver disorders when using certain medications. Genetic role in hepatotoxicity.	—

Secondary

Measure	Time frame
Risk profile of different medications	—

Countries

Netherlands

Outcome results