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Metabolic network activity and atrophy patterns in patients with parkinsonian disorders

Metabolic network activity and atrophy patterns in patients with parkinsonian disorders - Brain network activity and parkinsonism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON33983
Enrollment
45
Registered
2009-02-20
Start date
2009-09-28
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic Parkinson's disease multiple system atrophy parkinsonism

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients: fulfill the typical diagnostic criteria of IPD and MSA volunteers: normal clinical and neuropsychological examination, > 50 years

Exclusion criteria

Exclusion criteria: claustrophobia or other exclusion criteria for MRI scanning patients: other systemic disease who can cause listed complaints.

Design outcomes

Primary

MeasureTime frame
Network patterns will be extracted from the FDG PET data images. MRI examinations are used for to specify a precise degree of atrophy (VBM analysis) and tissue degeneration (DTI analysis). These PET and MRI output data will be used to define a specific disease related pattern for IPD and MSA.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)