Characterisation of regulatory T cells and cytokine production in children diagnosed with asthma

Characterisation of regulatory T cells and cytokine production in children diagnosed with asthma - Regulatory T cells in asthma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33976

Enrollment

120

Registered

2008-01-29

Start date

2008-03-06

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway hyperresponsiveness bronchusobstruction

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Diagnosis asthma for more than one year Use of inhaled corticosteroids for more than one year Lung function reversibility of more than 10% RAST test performed OR No asthma

Exclusion criteria

Exclusion criteria: The use of systemic immune modulating medication at the time of blood withdrawal and/or 6 weeks before blood withdrawal. Active infection at the time of blood withdrawal and/or the use of antibiotics at the time of blood withdrawal. OR Allergies and autoimmune diseases.

Design outcomes

Primary

Measure	Time frame
Number, phenotype and functionality of regulatory T cells in the peripheral blood.	—

Secondary

Measure	Time frame
Cytokine analysis in the peripheral blood	—

Countries

Netherlands

Outcome results