The effects of dopamine depletion on endogenous glucose production in healthy subjects

The effects of dopamine depletion on endogenous glucose production in healthy subjects - AMPT-CLAMP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON33972

Enrollment

Registered

2009-02-23

Start date

2008-11-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Interventions

One of the clamps will be performed after dopamine depletion with AMPT.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male Aged between 18 and 35

Exclusion criteria

Exclusion criteria: 1. Type I and II diabetes mellitus or any other chronic disease 2. Renal insufficiency or elevated liver enzymes 3. Family history of type II diabetes mellitus. 4. Primary dyslipidemia 5. Use of any drugs 6. Alcohol consumption in excess of 3 units per day or in the last 3 days before the clamp 7. History of drug abuse 8. Performance of vigorous exercise 9. History of psychiatric disorders

Design outcomes

Primary

Measure	Time frame
Glucose productions (suppression)	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)