The effect of a mixture of probiotics on constipation symptoms in pregnant women

The effect of a mixture of probiotics on constipation symptoms in pregnant women - Probiotics and constipation in pregnancy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON33971

Enrollment

Registered

2008-02-11

Start date

2007-12-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

constipation obstruction

Interventions

Study probiotics contain the following 6 probiotic strains: - Bifidobacterium bifidum - Bifidobacterium infantis - Bifidobacterium longum - Lactobacillus casei - Lactobacillus plantarum - Lactobacillu

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Pregnant women - Constipation as defined by the Rome III criteria - Third trimester

Exclusion criteria

Exclusion criteria: - Use of any laxatives 4 weeks before intake - Gastro-intestinal surgery in the medical history - Metabolic disease explaining constipation symptoms

Design outcomes

Primary

Measure	Time frame
Primary study outcome measurement: - Defecation frequency - Episodes of difficult defecation as mentioned in the Rome III criteria	—

Secondary

Measure	Time frame
Secondary study outcome measurements: - Stool consistency - Sensation of incomplete evacuation - Sensation of anorectal obstruction/ blockage - Manual manoeuvres to facilitate defecation - Abdominal pain - Adverse effects: bloating, flatulence, nausea, diarrhoea and bad taste - The presence of reflux episodes - The presence of uterovaginal prolapse - Use of Bisacodyl	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)