Early detection of bacteria in bloodstream infections using molecular diagnostics: implications for patient care

Early detection of bacteria in bloodstream infections using molecular diagnostics: implications for patient care - Early diagnosis of bloodstream infections

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON33903

Enrollment

340

Registered

2009-07-14

Start date

2009-10-22

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bloodstream infection sepsis

Interventions

After randomisation, test results obtained by either the PCR test or the conventional methods will be conveyed and antibiotic therapy will be adjusted accordingly. Demographic and follow-up data wil

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All consecutive patients of 18 years and older in the University Hospital Maastricht with a positive blood culture, including mentally incapacitated patients if their legal representatives signed informed consent for participation in this study.

Exclusion criteria

Exclusion criteria: A positive blood culture in the previous three days

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the reduction in time that broad spectrum or inappropriate antibiotic therapy is used.	—

Secondary

Measure	Time frame
Secondary outcomes are: - Length of hospital stay - Implementation of the therapy advised by medical microbiologists - Adverse effects of antibiotic use - Mortality - Economic evaluation	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)