depressieve symptomen anxiety and depression / mood disorder / affective disorders
Conditions
Interventions
Children are randomized to one of two treatment conditions, namely
(a) 10 weekly individual child CBT sessions and 2 parent sessions. The
following themes will be addressed: emphasizing the child*s
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria (parents): at least one of the biological parents is currently being treated for a depression (MDD, dysthymia) or an anxiety disorder (Social phobia SocP, Agoraphobia AP, Panic disorder PD, Generalized anxiety disorder GAD, Separation anxiety disorder SAD); informed consent. Inclusion criteria (offspring): age 8-18; being at risk for developing a depression or anxiety disorder, defined as meeting at least 2 of the 3 criteria of the High Risk Index (risk factors: female sex, 2 affected parents, suicide attempt of one of the parents; see Ch. 1) or reporting subthreshold symptoms of anxiety or depression, defined as scoring above the 80th percentile of the RCADS questionnaire (we chose a relatively high cutoff value for the RCADS, to enhance specificity); informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria (both parents): mental retardation; index parent is not fluent in Dutch; severe alcohol or substance use disorder; schizophrenia or other primary psychotic disorder; schizoaffective disorder; bipolar disorder BPD, Obsessive-compulsive disorder OCD, PTSD, only simple phobia SP. Exclusion criteria (offspring): mental retardation; not speaking Dutch fluently; severe alcohol or substance use disorder; current diagnosis of MDD, dysthymia, SocP, AP, PD, GAD, BPD, PTSD, OCD, SP; previous or current treatment for a DSM-IV psychiatric disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is the time to onset of depression or anxiety disorder in the offspring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures include number of days with depression or anxiety, child and parent symptoms, quality of life, and cost-effectiveness. In line with models on aetiology of mood and anxiety disorders as well as mechanisms of change during interventions, we selected possible mediators of treatment outcome, namely attribution style, coping, parent-child interaction and attachment, personality, optimism and self-esteem. | — |
Countries
Netherlands
Outcome results
None listed