Assessment of endothelial dysfunction and premature atherosclerosis in patients with recent onset Rheumatoid Arthritis, a longitudinal study

Assessment of endothelial dysfunction and premature atherosclerosis in patients with recent onset Rheumatoid Arthritis, a longitudinal study - Endothelial dysfunction measured by PWA in early RA, a longitudinal study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33873

Enrollment

Registered

2009-12-16

Start date

2009-02-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gewrichtsaandoeningen rheumatoid arthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: fulfill the ACR criteria for RA symptoms18 years not previously received disease modifying antirheumatic drugs.

Exclusion criteria

Exclusion criteria: pregnancy diabetes renal impairment( eGFR>60ml/min) recent surgery myocardial infarction or sepsis in the last three months

Design outcomes

Primary

Measure	Time frame
-Small artery elasticity -Intima media thickness -Advanced glycation end products in de huid	—

Secondary

Measure	Time frame
- soluble AGE receptor( s-RAGE) - endothelial activation markers such as VCAM, vWF, trombomoduline	—

Countries

Netherlands

Outcome results