arthrosis osteoarthritis
Conditions
Interventions
Experimental intervention
The experimental intervention comprises a 12-week exercise therapy program
aimed at 1) improving the knee joint stabilisation process, 2) muscle
strengthening and 3) functi
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All potential participants* eligibility will first be assessed by a physiatrist, using the following inclusion criteria: - diagnosis of knee OA according to the clinical ACR criteria, i.e.: knee pain and at least three of the following six: age > 50 years, morning stiffness
Exclusion criteria
Exclusion criteria: Co-morbidity which affects functional ability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure in this RCT is self-reported physical functioning as assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The WOMAC-pf is a commonly used questionnaire to assess the physical functioning of patients with OA, and has been shown to be reliable, valid and sensitive to change. | — |
Secondary
| Measure | Time frame |
|---|---|
| A number of secondary outcome measures are included in the study, reflecting both the assessment of disabilities in specific daily activities, the patient perspective, and relevant biomechanical factors. These measures are: perceived global effect (7-point Likert scale), pain intensity (0-10 NRS), stiffness (WOMAC), fatigue (0-10 NRS), Irrgang*s and Felson*s self-reported knee joint instability scales, questionnaires on rising and sitting down, walking and stair climbing, proprioception, laxity, isokinetic muscle strength of the upper leg (BioDex) and frontal plane alignment of the knee (goniometer). Body length and weight will be collected at all time points to assess changes in Body Mass Index | — |
Countries
Netherlands
Outcome results
None listed