The developmental and implantation potential of aneuploid and mosaic human embryos, as assessed in an in vitro model

The developmental and implantation potential of aneuploid and mosaic human embryos, as assessed in an in vitro model - Developmental potential of mosaic embryos

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33807

Enrollment

110

Registered

2007-12-17

Start date

2008-10-13

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

embryo aneuploidy

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Participation in study CCMO NL18499.000.07

Exclusion criteria

Exclusion criteria: No surplus embryos available

Design outcomes

Primary

Measure	Time frame
- In-vitro development: (early arrested, late arrested or developing), and in vitro implantation: invaded, attached or not-attached. - Total number of embryonic cells,proportion of aneuploid cells, and relative distribution between inner cell mass and trophoblast on day 10 after extended culture.	—

Secondary

Measure	Time frame
- Correlation between cytokine/trophic factor patterns expressed in (co-)culture media and the quality of development in vitro (early arrested, late arrested and developing embryos).	—

Countries

Netherlands

Outcome results