Conventional bronchoscopy vs. endosonography: A randomized prospective clinical study for the diagnosis of sarcoidosis

Conventional bronchoscopy vs. endosonography: A randomized prospective clinical study for the diagnosis of sarcoidosis - Diagnosing sarcoidosis: conventional bronchoscopy vs endosonography

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33798

Enrollment

140

Registered

2009-03-16

Start date

2009-03-30

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Besnier-Boeck disease lekenterm nvt

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with suspected pulmonary sarcoidosis (stage I/II) in whom a tissue diagnosis (presence of non-caseating granulomas) is indicated.

Exclusion criteria

Exclusion criteria: No informed consent Unable to undergo EUS/EBUS or bronchoscopy (e.g. esophageal strictures, respiratory insufficency) Unable to participate in the follow -up Contraindications for a lung or nodal biopsy (e.g. coagulopathy, thrombocytopenia) Pregnancy age under 18 years

Design outcomes

Primary

Measure	Time frame
The sensitivity of endo-sonography vs. bronchoscopy in the detection of non-caseating granulomas.	—

Secondary

Measure	Time frame
1. The role of a broncho-alveolar lavage (BAL) in addition to endo-sonography and conventional bronchoscopy for diagnosing sarcoidosis. 2. Complications in both study arms. 3. Patient tolerance for both study arms.	—

Countries

Netherlands

Outcome results