tandaandoeningen dental erosion wear
Conditions
Interventions
Enamel placed in an intra oral appliance will be brushed with 3 experimental
toothpastes and one conventional toothpaste. The volunteers wear these
appliances for 4 afternoons (1 toothpaste every af
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Adults with an ASA score of 1 with a rehabilited dentition.
Exclusion criteria
Exclusion criteria: An ASA score of 2 or higher, severe periodontal disease (Dutch periodontal screening indez, DPSI > 2) and an unrehabiliated dentition. Participants wearing a removable appliance in the upper jaw can not participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The loss of enamel due to erosion will be determined using Atomic Absorption Spectroscopy (AAS, calcium concentration) and molybdate UV-spectrophometry. With these techniques the loss of enamel can be calculated. Baseline measurements of the eroding solution will be performed. After exposing the samples to the eroding solution the calcium concentration of the solution is measured again. The differences in calcium concentration are an indication of the loss of enamel [Dijkman et al., 1983; Vieira et al., 2005]. | — |
Secondary
| Measure | Time frame |
|---|---|
| The pellicle adhered to the porcelain attached to the removable appliance will be analysed using SDS-page. The differences in protein composition between a pellicle exposed to toothpaste and normal pellicle will be determined | — |
Countries
Netherlands
Outcome results
None listed