Expression of factors involved in bile acid metabolism throughout the gastrointestinal tract Amendement: Expression of HIF-1alpha protein in upper GI tractus

Expression of factors involved in bile acid metabolism throughout the gastrointestinal tract Amendement: Expression of HIF-1alpha protein in upper GI tractus - GIBAM (=gastrointestinal bile acid metabolism)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33749

Enrollment

Registered

2007-11-06

Start date

2008-01-23

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

indirect Crohn's Disease no direct abberations are invistigated

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Subjects undergoing double balloon enteroscopy

Exclusion criteria

Exclusion criteria: Uncorrected coagulopathy at moment of enteroscopy. Subjects that do not fully understand the patient information folder (p.e due to insufficient comprehension of Dutch language)

Design outcomes

Primary

Measure	Time frame
To obtain insight in the expression of several nuclear receptors across the entire human gastrointestinal tract. Amendement: To obtain insight in the expression and amount of HIF-1 alpha in normal tissue of upper gastrointestinal tract	—

Secondary

Measure	Time frame
Possible association between nuclear receptors and pathologic diagnosis (i.e. Crohn*s disease)	—

Countries

Netherlands

Outcome results