Alcohol dependency depression
Conditions
Interventions
A part of the patients will be asked not to drink any alcohol 24 hours prior to
the research.
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Per group: (I) current DSM-IV diagnosis alcohol dependency and 6 month DSM-IV diagnosis of depression and/ or anxiety disorder; (II) 6-month DSM-IV diagnosis depression and/or anxiety disorder; (III) No DSM-IV psychiatric disorder
Exclusion criteria
Exclusion criteria: (a) the use of psychotropic medication except for selective serotonin reuptake inhibitors in stable dosage, (b) major internal or neurological disorder, (c) known contra-indications for MR investigations, such as the presence of metal objects (e.g. pacemaker, arteriovenous clips), or claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavioural data and Blood Oxygenated Level Dependent (BOLD)-response, recorded using fMRI, will be measured. These, and behavioural data are correlated with chronicity of alcohol dependence in order to investigate weather differences in several cognitive and motivational activities underlie the differences in chronicity of alcohol dependence. | — |
Secondary
| Measure | Time frame |
|---|---|
| nvt | — |
Countries
Netherlands
Outcome results
None listed