Cardiac sympathetic nervous system function and activity as a predictor for appropriate ICD therapy in patients with chronic heart failure

Cardiac sympathetic nervous system function and activity as a predictor for appropriate ICD therapy in patients with chronic heart failure - 123I-MIBG predicts appropriate ICD therapy in chronic heart failure

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33730

Enrollment

300

Registered

2009-04-07

Start date

2010-07-27

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure and fatal arrhytmias sudden cardiac death

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: *Left ventricular dysfunction (LVEF *35%) due to prior MI (at least 40 days post MI) *Left ventricular dysfunction (LVEF *35%) due to non-ischemic heart disease *NYHA functional class II and III *Receiving chronic optimal medical therapy *Reasonable expectation of survival with a good functional status of more than 1 year

Exclusion criteria

Exclusion criteria: *pregnancy *Left ventricular ejection fraction >35% *NYHA functional class I and IV *Not receiving chronic optimal medical therapy *Expected survival less than 1 year

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the trial will be appropriate ICD discharge or anti-tachycardia pacing.	—

Countries

Netherlands

Outcome results