Blood sampling after flow-mediated dilatation of the brachial artery: to do or not to do? The Balloon study.

Blood sampling after flow-mediated dilatation of the brachial artery: to do or not to do? The Balloon study. - The Balloon study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33710

Enrollment

Registered

2009-02-09

Start date

2009-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endothelial function vessel wall function assessement

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy individuals (males and females) aged 18 years and older

Exclusion criteria

Exclusion criteria: Smoking, any known risk factors for CVD or any known disorders or disease, chronic use of medication, use of medication prior to the investigation (e.g. NSAIDs), acute infection

Design outcomes

Primary

Measure	Time frame
Various parameters of coagulation and inflammation (vWF, platelet p-selectin, platelet activation, aPTT, PT, FVIII:C, D-dimer, prothrombin fragment 1+2, tissue factor, fibrinogen, platelet-monocytcomplex, C-reactive protein, monocyt chemotactic protein, IL-6, IL-8, IL-10, LDL-c, HDL-c, glucose, thrombocyte and leukocyte count, leukocyte differentiation) will be measured at several time points before and after FMD simulation. Does FMD influence these markers of coagulation and inflammation?	—

Measure

Time frame

Various parameters of coagulation and inflammation (vWF, platelet p-selectin, platelet activation, aPTT, PT, FVIII:C, D-dimer, prothrombin fragment 1+2, tissue factor, fibrinogen, platelet-monocytcomplex, C-reactive protein, monocyt chemotactic protein, IL-6, IL-8, IL-10, LDL-c, HDL-c, glucose, thrombocyte and leukocyte count, leukocyte differentiation) will be measured at several time points before and after FMD simulation. Does FMD influence these markers of coagulation and inflammation?

—

Secondary

Measure	Time frame
All laboratory parameters will be analysed separately to determine which parameters are influenced by FMD and how long a possible effect lasts.	—

Countries

Netherlands

Outcome results