The Role of brain area S1 in the perception of actions. A combined TMS and fMRI study on the functional connectivity of the human mirror neuron system.

The Role of brain area S1 in the perception of actions. A combined TMS and fMRI study on the functional connectivity of the human mirror neuron system. - The role of brain area S1 in the perception of actions

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33685

Enrollment

Registered

2008-12-17

Start date

2008-08-25

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gezonde proefpersonen It is a healthy subject study.

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Healthy males and females 2. Older than 18 years 3. Normal vision and hearing 4. Right-handed

Exclusion criteria

Exclusion criteria: 1. left-handedness or ambidexterity 2. drug or alcohol abuse 3. (history of ) significant medical, psychiatric or neurological conditions 4. history of head injury with loss of consciousness 5. metal in cranium 6. epilepsy or family history of epilepsy 7. cardiac pacemaker 8. infarcations 9. implanted medical pump 10. intracardiac lines 11. history of psychiatric illness 12. claustrophobia 13. (suspected) pregnancy 14. motor threshold > 69%, checked during the first session.

Design outcomes

Primary

Measure	Time frame
In this study we aim at shedding some light on the connections between the S1 brain area and the rest of the areas identifyed as part of the human MNS. Data collected when S1 is functioning normal and when it is disrupted is going to be analyzed by different techiques including traditional fMRI analysis tools and various methods of effective connectivity (PPI, Friston et al., 1994; DCM, Frackowiak and Friston, 2004; Granger Causality, Roebroeck, Formisano et al., 2005) to determine the pattern of connectivity and the causal effect of the target brain area in this pattern of connectivity.	—

Measure

Time frame

In this study we aim at shedding some light on the connections between the S1 brain area and the rest of the areas identifyed as part of the human MNS. Data collected when S1 is functioning normal and when it is disrupted is going to be analyzed by different techiques including traditional fMRI analysis tools and various methods of effective connectivity (PPI, Friston et al., 1994; DCM, Frackowiak and Friston, 2004; Granger Causality, Roebroeck, Formisano et al., 2005) to determine the pattern of connectivity and the causal effect of the target brain area in this pattern of connectivity.

—

Secondary

Measure	Time frame
n.v.t.	—

Countries

Netherlands

Outcome results