Pre-operative CT to improve delineation of the tumorbed in radiotherapy for breast cancer.

Pre-operative CT to improve delineation of the tumorbed in radiotherapy for breast cancer. - Delineation of the tumorbed in breast cancer.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33679

Enrollment

Registered

2008-07-07

Start date

2008-08-13

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Female patients with proven breast cancer, to be treated with breast conserving therapy, and a visible mass on mammography or ultrasound > 0.5 cm.

Exclusion criteria

Exclusion criteria: * All contra-indications for breast conserving therapy, i.e. pregnancy, multicentricity, inoperable disease, or a too large tumor in a relatively too small breast. * All contra-indications for intravenous contrast, i.e. iodine allergy, renal malfunction (kreatinine clearance 0.5 cm on mammography or ultrasound.

Design outcomes

Primary

Measure	Time frame
1) The percentage of the PTV-2 receiving 95% of the prescribed dose.	—

Secondary

Measure	Time frame
Other endpoints will be interobserver variation, as measured by 1) percent volume overlap of the PTVs; 2) difference in standard deviation of the average PTV-1 and PTV-2; 3) center of mass assay.	—

Countries

Netherlands

Outcome results