Factors influencing seizure threshold in Electroconvulsive Therapy

Factors influencing seizure threshold in Electroconvulsive Therapy - Factors influencing IST

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33666

Enrollment

Registered

2009-04-28

Start date

2009-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression depressive disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The sample of subjects contains all patients referred for ECT to the Alysis Zorggroep, location Rijnstate Hospital, Arnhem, the Netherlands

Exclusion criteria

Exclusion criteria: a. age

Design outcomes

Primary

Measure	Time frame
a. Level of IST and level of seizure threshold at every 6th ECT-session; b. Thickness of the skull and scalp; volume and amount of white matter hyperintensities (WMH); cortical thickness; volumes of gray and white matter; and volume of cerebrospinal fluid (CSF) using magnetic resonance imaging (MRI); c. Resting state functional connectivity using blood oxygen level-dependent signals (BOLD) on functional MRI (fMRI) of specific areas; d. Amount of axonal density (fractional anisotropy) as measured with Diffusion Tensor Imaging (DTI) of specific areas.	—

Measure

Time frame

a. Level of IST and level of seizure threshold at every 6th ECT-session; b. Thickness of the skull and scalp; volume and amount of white matter hyperintensities (WMH); cortical thickness; volumes of gray and white matter; and volume of cerebrospinal fluid (CSF) using magnetic resonance imaging (MRI); c. Resting state functional connectivity using blood oxygen level-dependent signals (BOLD) on functional MRI (fMRI) of specific areas; d. Amount of axonal density (*fractional anisotropy*) as measured with Diffusion Tensor Imaging (DTI) of specific areas.

—

Secondary

Measure	Time frame
The association between IST, *ST, demographic, clinical, and brain morphological and functional predictors and effectiveness of ECT.	—

Countries

Netherlands

Outcome results