A study of the effects of a novel ovarian stimulation regimen on embryo aneuploidy rates in IVF, and the impact of aneuploidy on implantation, as assessed in an in vitro model.

A study of the effects of a novel ovarian stimulation regimen on embryo aneuploidy rates in IVF, and the impact of aneuploidy on implantation, as assessed in an in vitro model. - Aneuploidy in IVF embryos and impact on implantation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33651

Enrollment

110

Registered

2007-12-17

Start date

2008-10-13

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

embryo aneuploidy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Female age * 39 years BMI

Exclusion criteria

Exclusion criteria: Indication for IVF male factor with a total motile sperm count

Design outcomes

Primary

Measure	Time frame
Proportion of chromosomally abnormal and mosaic day 3 embryos per patient based on PGS analysis.	—

Secondary

Measure	Time frame
- Number of oocytes retrieved, fertilization rates and proportion of morphologically high quality embryos on day 3. - Serum estradiol, LH, progesterone, androgen and hCG levels on cycle day 3 and day of hCG. - Developmental and in vitro implantation potential: invaded, attached or not-attached. - Total number of embryonic cells and proportion of aneuploid cells on day 10 after extended culture.	—

Countries

Netherlands

Outcome results