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A comparison of conventional adult out-of-hospital cardiopulmonary resuscitation against a concept with mechanical chest compressions and simultaneous defibrillation - LINC study

A comparison of conventional adult out-of-hospital cardiopulmonary resuscitation against a concept with mechanical chest compressions and simultaneous defibrillation - LINC study - LINC (LUCAS IN Cardiac Arrest) study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON33629
Enrollment
800
Registered
2008-07-08
Start date
2008-11-17
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

circulatory arrest sudden cardiac arrest

Interventions

Page numbers 8 of the study protocol Those randomized to treatment with LUCAS CPR will immediately be treated with manual compressions with minimized interruptions until the device is unpacked and

Sponsors

Jolife AB
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Circulatory arrest

Exclusion criteria

Exclusion criteria: 1. Traumatic cardiac arrest, including hanging 2. Age believed to be less than 18 years (no upper limit) 3. Known pregnancy 4. Defibrillated before LUCAS Chest Compressions System arrives at scene 5. Patients body size not fitting the LUCAS Chest Compression System

Design outcomes

Primary

MeasureTime frame
Page number 13 of the study protocol 8.1 PRIMARY ENDPOINT • Four hour survival from successful restoration of spontaneous circulation. This will generally mean survival to reach Intensive Care Unit (ICU) or Cardiac Care Unit (CCU).

Secondary

MeasureTime frame
Page number 12 of the study protocol 8.2 SECONDARY END POINTS • Restoration of spontaneous circulation (ROSC) defined as spontaneous palpable pulse. • Arrival to the emergency room with spontaneous palpable pulse • Survival to discharge from Intensive Care Unit (ICU) without severe neurological impairment (Cerebral Performance Category (CPC) 1 or 2). • Survival to hospital discharge without severe neurological impairment (CPC 1 or 2). • Survival 1 and 6 months after cardiac arrest without severe neurological impairment (CPC 1 or 2).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)