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Impaired regulation of Toll-like receptor-2 mediated T helper type responses in patients with inflammatory bowel disease

Impaired regulation of Toll-like receptor-2 mediated T helper type responses in patients with inflammatory bowel disease - immune dysregulation in IBD

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON33624
Enrollment
40
Registered
2009-04-21
Start date
2009-05-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease inflammatory bowel disease

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Crohn's disease diagnosed by standard endoscopic, histologic, and radiographic features, inactive disease as assessed by a CDAI

Exclusion criteria

Exclusion criteria: Patients that not fulfill the inclusion criteria

Design outcomes

Primary

MeasureTime frame
Differences in cytokine production and activated pathways between patients and controls in relation to carriage of the mutation, as determined by ELISA, realtime PCR and microarray analysis.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)