Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) for colorectal cancer screening

Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) for colorectal cancer screening - DWIBS for colorectal cancer screening

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33589

Enrollment

390

Registered

2008-07-15

Start date

2009-03-05

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon cancer Colorectal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Patients who are planned to undergo a colonoscopy in the UMC Utrecht because of suspected colorectal cancer, and having at least one of the following symptoms/signs: rectal bleeding, change in bowel habit, inexplicable weight loss, abdominal pain, and/or anemia -Age: 50 years and older -Written informed consent

Exclusion criteria

Exclusion criteria: -Patients with a general contraindication for MRI (including cardiovascular pacemakers, claustrophobia) -Patients who have had a previous malignancy -Patients who are pregnant or nursing -Patients in whom therapy has already started

Design outcomes

Primary

Measure	Time frame
Sensitivity, specificity, positive predictive value and negative predictive value of DWIBS (with 95% confidence intervals) for the detection of relevant colorectal lesions (carcinomas and polyps >= 6mm).	—

Secondary

Measure	Time frame
N.A.	—

Countries

Netherlands

Outcome results