focal liver lesion focal liver tumor
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Suspicion of focal liver lesions, both benign and malignant 2) Age > 18 years
Exclusion criteria
Exclusion criteria: - clinical query on liver MRI chart directed to other liver disease than focal liver lesions like cirrhosis, hepatitis or liver abces - previous liver surgery - a pacemaker - administration of a liver specific contrast agent within 2 weeks prior to the first MRI with Primovist - claustrophobia - hypersensitivity to active substance or any of the recipients of Gd-EOB-DTPA contrast - caution should be exercised in patients with clinically severe cardiovascular disease. myocardial infarction, uncontrolled hypertensia, instable angina pectoris, congestive hert failure, uncontrolled arhythmia's requiring medication - severe kidney failure (creatinin clearance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are sensitivity, specificity and positive predictive value for the detection and characterization of focal liver lesions | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity for the detection of hypo- and hypervascular lesions Sensitivity and specificity for the characterization between benign and malignant lesions Difference in ADC-value between benign and malignant lesions | — |
Countries
Netherlands
Outcome results
None listed