Deformation of Target Volume during Radiotherapy for Rectal Cancer: a repeat-CT study

Deformation of Target Volume during Radiotherapy for Rectal Cancer: a repeat-CT study - Repeat CT study in rectal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33552

Enrollment

Registered

2008-10-24

Start date

2008-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenocarcinoma of the rectum Rectal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: rectal adenocarcinoma T1-T4 (chemo-)radiotherapy followed by a total mesorectal excision

Exclusion criteria

Exclusion criteria: Previous abdominal or pelvic surgery Supine treatment position Previous irradiation of pelvis

Design outcomes

Primary

Measure	Time frame
The differences in day-to-day variation of the CTV (both random and systematic errors) will be used to design a margin recipe: based on the differences a formula will be given for the expansion from CTV to PTV, which will ensure a change for coverage of the target volume of at least 95% on every treatment day.	—

Secondary

Measure	Time frame
Based on the information of day-to-day variation, a protocol will be developed to apply adaptive radiotherapy to those patients: the radiotherapy plan will be adjusted according to the position of the target volume on that specific day.	—

Countries

Netherlands

Outcome results