hospital infections S. aureus colonization and infection
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: Provision of written informed consent and history of S. aureus infection, presence of toxin producing strains or wound colonisation
Exclusion criteria
Exclusion criteria: 1. A history of, or presence of diseases or other conditions in which no blood donation can take place (as judged by the investigator or the treating physician). 2.Evidence of having serum hepatitis or carrying the hepatitis B surface antigen or Hepatitis C antibodies or being HIV positive. 3. Abuse of alcohol or drugs or any other condition. 4. Pregnancy. 5. Positive drug screen for Benzodiazepines, methadone, metamphetamine, morphine, PCP, tricyclic antidepressants, amphetamines, cocaine, cannabinoids, barbiturates and ethanol 6. Subjects, who in the opinion of the investigator or the treating physician should not, for reasons of safety, participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is a detectable IgA or IgG response against staphylococcal antigens relevant for the development of therapeutic antibodies. The endpoint will be defined by the absence of a detectable IgA or IgG response against antigens relevant for the development of therapeutic antibodies. | — |
Countries
Netherlands
Outcome results
None listed