mineralen absorptie aandoeningen iron absorption iron bioavailability
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-40 years Body weight
Exclusion criteria
Exclusion criteria: Younger than 18 years of age and older than 40 years of age Post menopausal Using medicinal iron or related preparations Body weight > 65kg Pregnant or lactating People consuming chronic medication Use of vitamin and mineral supplements Blood donation in the last 6 months Subjects that in the past participated in studies with administration of stable isotope labels (iron).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the incorporation of 57Fe related to 58Fe into erythrocytes 14 d after administration and calculated based on isotope-dilution. | — |
Secondary
| Measure | Time frame |
|---|---|
| Whole blood will be collected at recruitment for the analysis of Hb, Hb type, serum ferritin (SF), transferrin receptor (TfR), C-reactive protein (CRP), erythropoietin (Epo), serum iron (SI), total iron binding capacity (TIBC), and transferrin saturation (TfSat). Anemia will be defined as a hemoglobin concentration | — |
Countries
Netherlands