Measuring the endothelial glycocalyx in cancer patients and determining the effect of chemotherapy

Measuring the endothelial glycocalyx in cancer patients and determining the effect of chemotherapy - Glycocalyx in cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33421

Enrollment

Registered

2009-02-09

Start date

2009-01-15

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer neoplasms

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Men and postmenopauzal women Aged over 18 years Informed consent Metastasized gastric or oesophageal or colon cancer, not yet started with chemotherapy Multiple myeloma;Healthy volunteers: healthy men or post-menopauzal women, aged over 18, informed consent

Exclusion criteria

Exclusion criteria: Diabetes mellitus Cardiovascular disease Medication used for the above mentioned diseases Pre-menopauzal women

Design outcomes

Primary

Measure	Time frame
Assessment of the glycocalyx in cancer patients and comparison to healthy controls by - Orthogonal Polarisation Spectroscopy (OPS) - Blood/urine parameters	—

Secondary

Measure	Time frame
The influence of chemotherapy on the primary parameters. Correlation of the glycocalyx state to the activation of the coagulation and clinical data after 3 months of follow-up.	—

Countries

Netherlands

Outcome results