MOODINFLAME - Early diagnosis, treatment and prevention of mood disorders targeting the activated inflammatory response system - Bipolar patients cohort

MOODINFLAME - Early diagnosis, treatment and prevention of mood disorders targeting the activated inflammatory response system - Bipolar patients cohort - MOODINFLAME - Bipolar patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33414

Enrollment

240

Registered

2009-07-20

Start date

2009-03-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: 18-65 years Both male and female Bipolar I disorder or Bipolar II disorder Preferentially euthymic (IDS-C

Exclusion criteria

Exclusion criteria: See inclusion criteria

Design outcomes

Primary

Measure	Time frame
Percentages of patients and controls with positively expressed genes in the monocytes and aberrant tryptophan parameters (positive/aberrant being defined as over one standard deviation of the level found in healthy controls).	—

Secondary

Measure	Time frame
Gene polymorphism determination and the various cytokine and S100 and BDNF determinations on the collected blood cells and HPA axis activity. Determine microglia activation in brain using PET.	—

Countries

Netherlands

Outcome results