MCKD
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: MCKD; Nephrectomy;
Exclusion criteria
Exclusion criteria: Heminephrectomy Conservatively managed Congenital abnormality contralateral kidney
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Previous medical history: parity of mother at birth, gestational age at birth, birth weight, birth length, singleton / multiple pregnancy, urinal and faecal continence, infection of urinary tract, obstipation Family history: diabetes (type), cardiovascular disease, hypertension, kidney disease / renal anomalies History: medication, smoking, alcoholintake Physical examination: height, weight, BMI, waist circumference (waist/hip ratio), blood pressure (measured three times in seating position with a Dinamap oscillometer) | — |
Secondary
| Measure | Time frame |
|---|---|
| Kidney ultrasound: kidneysize (compared to normal deviation), thickness of parenchyma, transverse dimension and if possible kidney length. Blood sampling: Cystatin-C, NGAL (neutrophil gelatinase-associated lipocalin), creatinine, uric acid, urea, HbA1C, glucose, Calcium and Phosphate Urinary sampling: TGF-beta1, sediment, screening, albumin/creatinine ratio and protein. | — |
Countries
Netherlands
Outcome results
None listed