inflammatory demyelinating neuropathy neuropathy
Conditions
Interventions
All patients and controls recieve 40 mg dexamethasone daily during 4 days
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Adult patients >
Exclusion criteria
Exclusion criteria: - Other diseases known to cause neuropathy - Use of drugs which are known to cause neuropathy - Neurophysiological evidence of carpal tunnel syndrome - Use of immunomodulatory drugs in the last 6 months or IVIg in the last 2 months. - Refusal to give informed consent or withdrawal of previously given permission - Legally incompetent adult
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Change in excitability indicating hyperpolarization 2. Change in severity and number of conduction blocks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Conduction velocity 2. MRC sum score (muscle strength) 3. INCAT sensory sum score (sensory deficit score) 4. ALDS (Amsterdam Linear Disability Scale) 5. INCAT disability scale (a frequently used disability scale in inflammatory neuroapathies) 6. any adverse event or reaction | — |
Countries
Netherlands
Outcome results
None listed