cognitieve en aandachtsstoornissen en -afwijkingen depression memory complaints
Conditions
Interventions
None listed
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: depressive disorder and eligible for ECT treatment
Exclusion criteria
Exclusion criteria: • age 65 jaar • major medical conditions that may interfere with the study procedures: cancer, cerebrovascular disorders, organic psychiatric syndromes, active drug abuse, mental retardation, dementia and other neurodegenerative disorders. Psychopathology will be assesses by a psychiatric interview. • Illiteracy • any condition which in the opinion of the (co-) investigator might interfere with the evaluation of the study objectives
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. association between the epigenetic changes like DNA-methylation and histone modifications of certain genes in blood lymphocytes and the cognitive side effects of ECT treatment 2. association between the epigenetic changes like DNA-methylation and histone modifications of certain genes in blood lymphocytes and the response to ECT. The endpoint of the study will be 6 weeks after cessation of the ECT treatment. | — |
Countries
Netherlands
Outcome results
None listed