The effect of lower body negative pressure on cerebral autoregulation in young and elderly healthy volunteers

The effect of lower body negative pressure on cerebral autoregulation in young and elderly healthy volunteers - ELOCA study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON33320

Enrollment

Registered

2009-05-29

Start date

2010-05-26

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthostasis

Interventions

Lower body negative pressure (LBNP).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - age: 18-35 years and >70 years - non-smoking - body mass index: 18-28 kg/m2 - length: 160-190 cm

Exclusion criteria

Exclusion criteria: - medical history of cardiovascular disease, diabetes mellitus, pulmonary disease, neurological disease, malignant disease, venous insufficiency - alcohol use >3 units / day - use of systemic medication - cognitive impairment (MMSE score

Design outcomes

Primary

Measure	Time frame
Change in (regional) cerebral blood flow and cerebral blood volume.	—

Secondary

Measure	Time frame
Cerebral blood flow velocity of main feeding cerebral arteries, continuous blood pressure and heart frequency.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)