'OSAS' and 'sleep apnea'
Conditions
Interventions
patients with mild OSAS will receive a structered program, consisting of
exercise training and dietary advice for 24 weeks, with follow-up measurements
after 12 and 24 weeks.
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Individuals who have been subjected to polysomnography and are diagnosed as having mild (5 20 years 3. Body mass index (BMI) > 25
Exclusion criteria
Exclusion criteria: 1. Patients with previous treatment for OSAS (continuous positive airway pressure (CPAP), oral-appliance therapy, uvulopalatopharyngoplasty (UPPP)) 2. Morphologic abnormalities of the upper airway (e.g., a compromised nasal passage, enlarged tonsils or adenoids, or upper airway soft-tissue or craniofacial abnormality) 3. Endocrine dysfunction (hypothyroidism, acromegaly, or pituitary adenoma) 4. Reported or documented severe cardiac- or pulmonary co-morbidity (daytime respiratory insufficiency, severe chronic obstructive pulmonary disease (COPD), heart failure, coronary disease, or severe cardiac arrhythmias) 5. Psychiatric disorders (e.g., depression or schizophrenia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility assessed by patient compliance to the treatment: number of patients dropping out of the program; percentage training sessions attended by each patient; usage of the pedometer; amount of times patient fills in the diary. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fat-free mass, weight, subjective daytime sleepiness, health related quality of life, the influence of excessive sleep on physical-, mental- and social functioning in daily life, symptoms of current depression and anxiety, activities of daily living, compliance with treatment, intima-media thickness (IMT) of the carotid arteries, Advanced Glycation Endproducts (AGEs). | — |
Countries
Netherlands
Outcome results
None listed