Coagulation disorders in trauma patients

Coagulation disorders in trauma patients - ALARM-BLEEDING study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33294

Enrollment

120

Registered

2009-09-23

Start date

2009-11-25

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatisch letsel accidental injury Traumatic injury

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Trauma patients treated by a trauma team that received medical care in the shock room Age > 18 years

Exclusion criteria

Exclusion criteria: Patients with haemostatic abnormalities or deficiencies

Design outcomes

Primary

Measure	Time frame
The incidence proportion of bleeding in trauma patients as reflected by blood transfusions and/or surgical- or radiological interventions to control bleeding.	—

Secondary

Measure	Time frame
* Level of comparison of INTEM clotting time and aPTT and FIBTEM and Clauss test for fibrinogen. * Age, gender, length, body weight, hematocrit, hemoglobin, leukocyte count, CRP, highest creatinine, ISS, predictive outcome scores * Temperature upon arrival at the emergency department and temperature dynamics over the first 24 hours post-trauma. * Level of fibrinolysis using ROTEM APTEM test * Tissue factor, thrombin, thrombin-antithrombin complexes (TAT), antithrombin III (AT III), D-dimers and protein C * Medicine use: use of drugs that influence coagulation * Administration of blood products and fluid, urine production	—

Measure

Time frame

* Level of comparison of INTEM clotting time and aPTT and FIBTEM and Clauss test for fibrinogen. * Age, gender, length, body weight, hematocrit, hemoglobin, leukocyte count, CRP, highest creatinine, ISS, predictive outcome scores * Temperature upon arrival at the emergency department and temperature dynamics over the first 24 hours post-trauma. * Level of fibrinolysis using ROTEM APTEM test * Tissue factor, thrombin, thrombin-antithrombin complexes (TAT), antithrombin III (AT III), D-dimers and protein C * Medicine use: use of drugs that influence coagulation * Administration of blood products and fluid, urine production

—

Countries

Netherlands

Outcome results