In vivo imaging of amyloid-beta deposition in Alzheimer's disease

In vivo imaging of amyloid-beta deposition in Alzheimer's disease - Amyloid imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33273

Enrollment

Registered

2009-06-09

Start date

2009-07-21

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hersenaandoening cognitive dysfunction dementia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Diagnosed with probable Alzheimer's disease - Diagnosed as memory complainer - Capable of giving informed consent

Exclusion criteria

Exclusion criteria: - Contra-indication to MRI scanning: • Claustrophobia • Pacemakers and defibrillators • Nerve stimulators • Intracranial clips • Intraorbital or intraocular metallic fragments • Cochlear implants • Ferromagnetic implants • Hydrocephaluspump • Intra-utrine device • An iron wire behind the teeth • Permanent make-up • Tattoos above the shoulders - MMSE

Design outcomes

Primary

Measure	Time frame
The main study parameter will be a qualitative measure of the presence of distinct hypointense cortical foci and an inhomogeneous aspect of the cortex.	—

Secondary

Measure	Time frame
The secondary study parameter will be a quantitative measure of susceptibility related changes in the cortex.	—

Countries

Netherlands

Outcome results