1 coronary artery bypass surgery 2 atherosclesis
Conditions
Interventions
None listed
Sponsors
Maquet cardiopulmonary
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * To have the right indication. * Body surface area between 1.7 and 2.0 m². * Age 20-80. * Pre-operative normal sinus rhythm and AV-conduction time. * Pre- operative haemoglobin > 6.5 mmol/L. * Patient must be able to give written informed consent
Exclusion criteria
Exclusion criteria: * Transfusion of blood products shorter than seven days before the operation. * Re- operations * Coagulation problems due to the use of thrombolytic agents less than 48 hours before the operation. * Thrombocytopenia (platelet count below 100,000 per ml) * Patient with hereditary hematological/ coagulation disorders * Insulin dependent diabetes * Using corticosteroid medication, use of corticosteroids before the surgery, or during the study period. * Emergency surgery * History of atrial fibrillation or other atrial arrhytmias eg (1 ° block, paroxysmal atrial tachycardia, atrial flutter) *Use of aspirin within 7 days or Plavix within 5 days or other anti platelet agents (including non steroid anti-inflammatory medicaments) within 48 hours. * Patients who are currently (within the last two months) participating in another clinical trail.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary goal The primary goal is to evaluate whether the use of miniaturised systems reduces the need for homologous blood transfusions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary goal The secondary goal is to evaluate whether the use of miniaturised systems reduces the time to extubation post-operatively. To this end an early extubation protocol is used to standardize the extubation process. | — |
Countries
Netherlands
Outcome results
None listed