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The influence of age dependent changes in muscle components, muscle stiffness and neuro muscular control on the performance during a point-to-point reaction time test

The influence of age dependent changes in muscle components, muscle stiffness and neuro muscular control on the performance during a point-to-point reaction time test - Influence of aging on muscles

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON33211
Enrollment
60
Registered
2009-07-16
Start date
2009-08-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

natuurlijke veranderingen door verouderingsprocessen Aging muscle performance

Interventions

None listed

Sponsors

Vrije Universiteit Brussel (Departement Gerontologie & Geriatrie)
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 31 as well as 70 year and above Healthy disposition stated by subject Normal cognition (Mini-Mental-State Examination >26/30),

Exclusion criteria

Exclusion criteria: Neurological disease, Inflammatory pathalogy Musculoskeletal disorders of upper extremities Metal in body Pace maker in body Sport on competitive level

Design outcomes

Primary

MeasureTime frame
Component 1 - Primary study parameters: Reactiontime (Descision time and Movement Time), co-contractionratio (sEMG activitivity ratio M Biceps/Triceps Brachii) and movements pattern (acceleratie-deceleratie M. Biceps & Triceps Brachii) during RT-test.

Secondary

MeasureTime frame
Component 2- primary outcome: Elasticity muscle tendon en musclefibers M. Biceps & Triceps Brachii. Component 3- primary outcome: Bandwith of intra-muscular (non fat) collagen Component 4 - primary outcome: Level of circulating markers of inflammation (Cytokines, Heat Shock Proteins) and non-enzymatic cross-links (AGEs) determined by ELISA and/or HPLC)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)