The ocular Vestibular Evoked Myogenic Potentials (oVEMPs) in patients with BRIC type 1 disease

The ocular Vestibular Evoked Myogenic Potentials (oVEMPs) in patients with BRIC type 1 disease - oVEMP test in BRIC type 1 disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33203

Enrollment

Registered

2009-04-28

Start date

2009-07-06

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

BRIC type 1 dizzyness vertigo

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with a mild phenotype of FIC1 disease, BRIC type 1, with 2 known mutations in the ATP8B1-gene and clinically one episode of low or normal *-glutamyl transpeptidase (GGT) cholestasis. Age * 18 years

Exclusion criteria

Exclusion criteria: An interfering cause of vertigo History of eye-motility disorders Audiometrically defined conductive hearing loss of more than 20 dB NHL at 500 Hz

Design outcomes

Primary

Measure	Time frame
The main study parameters are the amplitude and the threshold of the oVEMP response.	—

Secondary

Measure	Time frame
Other characteristics of the oVEMP-response, such as the latencies of the various peaks in the response. All variables will be studied in relation to the level of the oVEMP-evoking sound stimulus.	—

Countries

Netherlands

Outcome results