Expression of CCL25 and CCR9 in human colon in IBD/PSC patients

Expression of CCL25 and CCR9 in human colon in IBD/PSC patients - PSColon

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33155

Enrollment

Registered

2009-11-02

Start date

2009-05-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic cholestatic liver disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age: >18 Established diagnosis of PSC Established diagnosis of IBD Established diagnosis of infectious enterocolitis

Exclusion criteria

Exclusion criteria: Bleeding diathesis Inability to give informed consent

Design outcomes

Primary

Measure	Time frame
Expression of CCL25 in human colon by immunohistochemistry.	—

Secondary

Measure	Time frame
Difference in presence of CCL25 and/or CCR9+ lymphocytes in double stained colonic biopsies between patients and controls. Quantitative analyses of CCL25 mRNA expression in colon and CCR9+ T-cells in peripheral blood of patients and controls.	—

Countries

Netherlands

Outcome results