the Application of an Electronic Nose in the Early detection of ASpergillosis

the Application of an Electronic Nose in the Early detection of ASpergillosis - the AENEAS study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33126

Enrollment

Registered

2009-11-24

Start date

2009-09-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fungal pneumonia invasive pulmonary mycosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients that 1. are 18 years of age or older 2. will undergo treatment for a hematological malignancy expected to result in grade 4 neutropenia (according to CTCAE 3.0, i.e.

Exclusion criteria

Exclusion criteria: 1. a previously diagnosed invasive mycosis, or 2. the inability to perform the breathing manoeuvre needed for eNose-analysis of exhaled air

Design outcomes

Primary

Measure	Time frame
To establish the accuracy with which the Cyranose* can discriminate patients with probable or proven invasive pulmonary aspergillosis from neutropenic controls with fever.	—

Secondary

Measure	Time frame
To establish whether neutropenic patients with fever but no sign of aspergillosis can be discriminated from healthy subjects, thus measuring the combined influence of chemotherapy, neutropenia, antibiotics and fever on the algorithm used for the main objective.	—

Countries

Netherlands

Outcome results