minerale absorptie aandoeningen iron absorption
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: female 18-40 year Weighing no more than 65kg Non-pregnant, non-lactating Apparently healthy free from chronic illness or receiving chronic medication No medicinal nor supplemental iron at time of entry onto the study No intake of vitamin or mineral supplements in the last 2 weeks prior the study, or willingness to discontinue. Subjects has not made blood donations in the last 6 months Subjects has not participated in studies using stable isotopic labels (iron) in the past.
Exclusion criteria
Exclusion criteria: younger than 18 years or older than 40 weighing more than 65kg Use of mineral and vitamin supplements People consuming chronic medication pregnant or lactating Blood donation inthe last 6 months Participation to stable isotope studies (iron) in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Iron absorption will be estimated using stable-isotope techniques where incorporation of 57Fe and 58Fe into erythrocytes is measured 14 d after administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Whole blood will be collected at recruitment for the analysis of Hb, serum ferritin (SF), C-reactive protein (CRP). Anemia will be defined as a hemoglobin concentration | — |
Countries
Netherlands