The neural basis of congitive-emotional processing in people with an at-risk mental state for developing psychosis

The neural basis of congitive-emotional processing in people with an at-risk mental state for developing psychosis - The neural basis of at-risk menatl state for psychosis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON33062

Enrollment

Registered

2009-10-20

Start date

2009-12-14

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis schizophrenia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - healthy individuals, male and female with IQ in the normal range and with normal or corrected to normal vision. - between 18 and 45 years old

Exclusion criteria

Exclusion criteria: - neurological problems (incl. epilepsy) - use of drugs that may influence the task - contra indications for fMRI will lead to exclusion, fMRI-exclusion criteria: - MR incompatible implants in the body (such as ear prothesis or other metal implants) - any risk of having metal particles in the eye - tattoos containing red pigments - (suspected) pregnancy - claustrophobia - the refusal to be informed of structural brain abornamilities that could be detected during the experiment.

Design outcomes

Primary

Measure	Time frame
In this study brain activation during cognitieve processing will be investigated in two separate sessions, separated by 8 months. Questionnaire scores will be linked to brain activation. Through diagnostic interviews and symptom evalutions 2 years after the first fMRI scan will be conducted, to evaluate whether fMRI activation was predictive of the clinical state 2 years later.	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results