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Caregiving fathers: do hormones help them along?

Caregiving fathers: do hormones help them along? - The fathers-to-be study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON33016
Enrollment
90
Registered
2010-07-02
Start date
2010-10-20
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

het gaat niet om een aandoening maar om de hormonale invloed op de zorg voor kinderen. caring fatherhood

Interventions

The participants will receive during the prenatal labstudy twice an (synthetic) hormonal treatment, Oxytocin and Desmopressin, and once a placebo (saline).

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The participants will be 60 expectant nulliparous fathers and 30 non-expectant childless men as controls; physically and mentally healthy men; in a heterosexual relationship and living together with this partner

Exclusion criteria

Exclusion criteria: Unhealthy men, men with previous children or stepchildren, men expecting twins, single men.

Design outcomes

Primary

MeasureTime frame
The main interest of the study is the relationship between hormone levels and caregiving attitudes, interest, and behavior. Besides looking at the relationships between basal levels of 5 different hormones (i.e. oxytocin, vasopressin, testosterone, prolactin, and cortisol) and the caregiving factors, we will also look at how altering the levels of two of the hormones affects these relationships. Therefore, we plan to conduct an experiment that will be carried out three times for each participant. Each session will be used to test the effects of the elevation of one of these hormones or the placebo. The hormones that are tested are oxytocin, and vasopressin. These hormones are administered through an intranasal spray, and past research has shown that hormonal alterations of this kind can affect behavior. In the experiment we measure indicators of the subjects* caregiving interest in a virtual world. We expect that the participants treated with hormonal spray will show more caregiving interest as compared to the placebo condition. We expect the fathers-to-be to primed for caregiving and therefore to show a larger response towards the sprays as compared to the childless controls. Specific hypotheses concerning the hormone levels are: We hypothesize that oxytocin will be positively related to caregiving interest and caregiving behavior. We hypothesize that prolactin will be positively related to caregiving interest and caregiving behavior. We hypothesize that cortisol will be negatively related to oxytocin, and to caregiving interest and caregiving behavior. We hypothesize that testosterone will be negatively related to caregiving interest and caregiving behavior. We hypothesize that vasopressin has a greater role than oxytocin in actual paternal caregiving.

Secondary

MeasureTime frame
Whether differences in caregiving attitudes, interest, and behavior are a result of the indirect influences of the investigated (basal and/or applied) hormones on emotion recognition, implicit attitudes and/or prosocial behaviors, or may be the cause of genderidentity, or personality influences.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)