Cardiac arrest heart attack
Conditions
Interventions
Mechanical chest compression vs conventional manual chestcompressions in a
resuscitation. see appendix 1 and 2 from LIHA protocol
Sponsors
Sint Antonius Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: IHCA (In-hospital cardiac arrest)
Exclusion criteria
Exclusion criteria: • Age believed to be less than 18 years • Known pregnancy • Patients body size is not fitting in the LUCAS • Patients 24 hours post trombolysis for any cause • Non-witnessed cardiac arrest • Resuscitation in operating room
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint is the ROSC for more than 20 minutes of witnessed In-hospital cardiac arrests when resuscitated with the LUCAS Chest Compression System. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objectives are to show superiority in survival for the modified method with the LUCAS chest compression system compared to the conventional manual resuscitation method in patients suffering from witnessed in-hospital cardiac arrest by measuring the following secondary endpoints: ·Restoration of spontaneous circulation (ROSC) defined as spontaneous palpable pulse 24 hours ·Survival to hospital discharge without severe neurological impairment (CPC 1 or 2). ·Survival 1 and 6 months after cardiac arrest without severe neurological impairment (CPC 1 or 2). ·Primary endpoint comparing LUCAS protocol starting in less than 6 minutes vs more than 6 minutes from emergency call Tertiary objectives ·Survivors have less post-resuscitation subendocardial infarction measured with delayed contrast enhancement on MRI when resuscitated with LUCAS compression system compared to manual chest compressions ·Degree of transmural infarction after resuscitation diagnosed with delayed contrast enhancement is predictive for functional improvement in myocardial function after 6 months | — |
Countries
Netherlands
Outcome results
None listed