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The neural mechanisms involved in curiosity and uncertainty reduction

The neural mechanisms involved in curiosity and uncertainty reduction - curiosity and uncertainty reduction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON32982
Enrollment
24
Registered
2009-03-16
Start date
2009-10-18
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gezonde brein nvt

Interventions

None listed

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults subjects (18-30 years of age) with no history of neurological disorder/disease and no counter-indications to MRI will be included in this study. All participants will be right-handed native Dutch speakers with normal vision or contact lenses

Exclusion criteria

Exclusion criteria: Potential participants will be prescreened for contraindications for fMRI, which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy. They will additionally be prescreened for head trauma, history of neurological or psychiatric illness and/or use of psychotropic medications. Because of the difficulties in interpreting cognitive studies in subjects with Dutch as a second language, only native-Dutch speakers will be asked to participate in the study. Finally, left-handed individuals will be excluded from the study because some left-handers have substantially different brain organization relative to right-handers.

Design outcomes

Primary

MeasureTime frame
The main study parameters are the significant clusters of brain activation associated with uncertainty and those associated with uncertainty reduction. The main behavioral study parameter is the number of items recalled in the free recall test as a function of condition (prior uncertainty vs. no prior uncertainty; see section 4).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)