Narrow band imaging versus white light enteroscopy for detection of inflammation in small bowel in patients with Crohn*s disease

Narrow band imaging versus white light enteroscopy for detection of inflammation in small bowel in patients with Crohn*s disease - NBI vs. WLE for detection of small bowel Crohn's disease activity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32943

Enrollment

Registered

2009-10-01

Start date

2009-07-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease localisation in small bowel gastrointestinal bleeding

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Individuals eligible for inclusion are patients with age 18 years or older, with known Crohn's disease or iron deficiency anemia.

Exclusion criteria

Exclusion criteria: Age under 18 years of age. Medical and psychological contraindications for enteroscopy. Patients unable or not willing to give informed consent.

Design outcomes

Primary

Measure	Time frame
Comparison of NBI enteroscopy with WLE in detection and grading of CD inflammation in small bowel, using findings on histopathology as the gold-standard for mucosal inflammation.	—

Secondary

Measure	Time frame
Correlation of endoscopic findings with clinical findings. Correlation of endoscopic findings with immunohistochemical analysis of immunocompetent cells and mRNA levels of proinflammatory cytokines.	—

Countries

Netherlands

Outcome results